General Information of Binding Target of SBP (BTS) (ID: ST00340)
BTS Name
BPP
Synonyms
Baseplate protein
BTS Type
Protein
Gene Name
bpp
Organism
Lactococcus phage TP901-1
UniProt ID
Q9G096
UniProt Entry
Q9G096_9CAUD
PFam
PF18338 ; PF08931
Gene ID
921038
Sequence
MASIKKVYRGMKNGAETINDDLEAINSELTSGGNVVHKTGDETIAGKKTFTGNVEVNGSL
TLPTKSWSGELGGGIILSLRKKGTTVEYSIGGEISSSILANSNLVNRSVPNEFCPRNRCS
LVGHMVGGWNAFHIDIPSSGVCQWFGPTASSGTPRGTGTYPID
Sequence Length
163
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
DARPin anti-BPP clone 18 Research Inhibitor Kd: 7.5 nM Lactococcus lactis infection
SBP Info
[1]
DARPin anti-BPP clone 19 Research Inhibitor Kd: 3.5 nM Lactococcus lactis infection
SBP Info
[1]
DARPin anti-BPP clone 20 Research Inhibitor Kd: 1.6 nM Lactococcus lactis infection
SBP Info
[1]
References
1 Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode. J Biol Chem. 2009 Oct 30;284(44):30718-26.