General Information of Binding Target of SBP (BTS) (ID: ST00308)
BTS Name
SrcB subgroup Lck-Src-homology 2
Synonyms
Lck SH2
BTS Type
Protein
Organism
Homo sapiens (Human)
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Monobody anti-Hck-SH2/Lck-SH2 clone 1 Research Inhibitor Kd: 3169 nM Tools for dissecting SFK functions in normal development and signaling
SBP Info
[1]
Monobody anti-Hck-SH2/Lck-SH2 clone 2 Research Inhibitor Kd: 2508 nM Tools for dissecting SFK functions in normal development and signaling
SBP Info
[1]
Monobody anti-Lck-SH2/Hck-SH2 clone 1 Research Inhibitor Kd: 14 nM Tools for dissecting SFK functions in normal development and signaling
SBP Info
[1]
Monobody anti-Lck-SH2/Hck-SH2 clone 3 Research Inhibitor Kd: 19 nM Tools for dissecting SFK functions in normal development and signaling
SBP Info
[1]
References
1 Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies. J Mol Biol. 2017 May 5;429(9):1364-1380.