Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00294) | ||||||
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| BTS Name |
Interleukin-21 receptor
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| Synonyms |
IL-21 receptor; IL-21R; Novel interleukin receptor; CD antigen CD360
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| BTS Type |
Protein
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| Family |
Type I cytokine receptor family;
Type 4 subfamily |
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| Gene Name |
IL21R
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| Organism |
Homo sapiens (Human)
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| Function |
This is a receptor for interleukin-21.
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| Gene ID | ||||||
| Sequence |
MPRGWAAPLLLLLLQGGWGCPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKD
EATSCSLHRSAHNATHATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKP APPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDS RSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLL LLLLVIVFIPAFWSLKTHPLWRLWKKIWAVPSPERFFMPLYKGCSGDFKKWVGAPFTGSS LELGPWSPEVPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPKPSFWPTAQNSGG SAYSEERDRPYGLVSIDTVTVLDAEGPCTWPCSCEDDGYPALDLDAGLEPSPGLEDPLLD AGTTVLSCGCVSAGSPGLGGPLGSLLDRLKPPLADGEDWAGGLPWGGRSPGGVSESEAGS PLAGLDMDTFDSGFVGSDCSSPVECDFTSPGDEGPPRSYLRQWVVIPPPLSSPGPQAS |
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| Sequence Length |
538
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| scFv anti-IL-21R Random-14 | Research | Binder | Kd: 17.5 nM | Research tool | [1] | |
| scFv anti-IL-21R Random-15 | Research | Binder | Kd: 1.9 nM | Research tool | [1] | |
| scFv anti-IL-21R Random-2 | Research | Binder | Kd: 11.5 nM | Research tool | [1] | |
| scFv anti-IL-21R Random-5 | Research | Binder | Kd: 5.1 nM | Research tool | [1] | |
| scFv anti-IL-21R Random-7 | Research | Binder | Kd: 4.2 nM | Research tool | [1] | |
| scFv anti-IL-21R Random-97 | Research | Binder | Kd: 10.8 nM | Research tool | [1] | |