Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00225) | ||||||
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| BTS Name |
Protein DETOXIFICATION
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| Synonyms |
Multidrug and toxic compound extrusion protein
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| BTS Type |
Protein
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| Family |
Multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family
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| Organism |
Sorghum bicolor (Sorghum) (Sorghum vulgare)
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Sequence |
MCNAAAGTDSSLPAPAAPFGSFKAAAHQLLHPVDGDEGSGGHALQLSKVAGEARAIGRVS
VPMAVTGLVMYSRALISMLFLGRLGELALAGGSLALGFANITGYSVLSGLALGMEPICGQ AFGARRGKLLALALHRTVLLLLAVALPISALWVTSTGYVLKLLGQDEGVADAAQTFAAYA SADLAVLAVLHPLRVYLRSQNLTLPITACSLFSVLLHGPINYLLVVRLQMGVAGVALAVA LTDLNLLLALLCFLAISGAHRDSWVGPTLDCLRGWPEMLRLAVPTATAVCLEWWWYELMI VLSGLLANPRATVASMGILIQATSLVYVFPSSLGQGASTRVSHQLGAGRPAGARRAAGAA LSIGVGVGLAAAAFMVSVRSHWGRMFTSDADILRLTAVALPIAGLCELGNCPQTAGCGVL RGSARPASGARINLASFYLVGMPVGVALAFGARLGFAGLWLGLLAAQAACAVWMARAVAA TDWDVEVGRAKELTKASSSSSSNSHSECNTTSSASASDVTTVIATSNSAAGCKKNNGGYV PISESCSNDSELEKLEEGLMTSDDIPSASVSGSACGGDTDAVVREQNRGSGNSCNDSGAA GTAATEGKEQRKGGSEERGPLISVSDGEHDGDSRGGGGQV |
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| Sequence Length |
640
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Nanobody anti-sbMATE clone 80 | Research | Modulator | Kd: 12200 nM | Research tool | [1] | |
| Nanobody anti-sbMATE clone 81 | Research | Modulator | Kd: 23900 nM | Research tool | [1] | |
| Nanobody anti-sbMATE clone 83 | Research | Modulator | Kd: 3300 nM | Research tool | [1] | |
| Nanobody anti-sbMATE clone 86 | Research | Modulator | Kd: 173.6 nM | Research tool | [1] | |
| Nanobody anti-sbMATE clone 93 | Research | Modulator | Kd: 26100 nM | Research tool | [1] | |
| Nanobody anti-sbMATE clone 94 | Research | Modulator | Kd: 99.5 nM | Research tool | [1] | |