General Information of Binding Target of SBP (BTS) (ID: ST00214)
BTS Name
Vesicular glutamate transporter 1
Synonyms
VGluT1; Brain-specific Na(+-dependent inorganic phosphate cotransporter; Solute carrier family 17 member 7
BTS Type
Protein
Family
Major facilitator superfamily;
Sodium/anion cotransporter family;
VGLUT subfamily
Gene Name
Slc17a7
Organism
Rattus norvegicus (Rat)
Function
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
UniProt ID
Q62634
UniProt Entry
VGLU1_RAT
PFam
PF07690
Gene ID
116638
Sequence
MEFRQEEFRKLAGRALGRLHRLLEKRQEGAETLELSADGRPVTTHTRDPPVVDCTCFGLP
RRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQKAQFNWDPETVGLIH
GSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYGCVIFVRILQG
LVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYV
YGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPVTKFNTPWRRFFT
SMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPIGGQ
IADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGYSHSKGVAISFLVLAVGFSGFAIS
GFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHKTREEWQYVFLIASLVHY
GGVIFYGVFASGEKQPWAEPEEMSEEKCGFVGHDQLAGSDESEMEDEVEPPGAPPAPPPS
YGATHSTVQPPRPPPPVRDY
Sequence Length
560
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Nanobody anti-VGLUT1 clone 1 Research Inhibitor N.A. Biochemical agents
SBP Info
[1]
Nanobody anti-VGLUT1 clone 10 Research Inhibitor N.A. Tools for cell biology and neuroscience
SBP Info
[1]
Nanobody anti-VGLUT1 clone 11 Research Inhibitor N.A. Biochemical agents
SBP Info
[1]
Nanobody anti-VGLUT1 clone 2 Research Inhibitor N.A. Biochemical agents
SBP Info
[1]
Nanobody anti-VGLUT1 clone 3 Research Inhibitor N.A. Biochemical agents
SBP Info
[1]
Nanobody anti-VGLUT1 clone 4 Research Inhibitor N.A. Biochemical agents
SBP Info
[1]
Nanobody anti-VGLUT1 clone 5 Research Inhibitor N.A. Biochemical agents
SBP Info
[1]
Nanobody anti-VGLUT1 clone 6 Research Inhibitor N.A. Biochemical agents
SBP Info
[1]
Nanobody anti-VGLUT1 clone 7 Research Inhibitor N.A. Tools for cell biology and neuroscience
SBP Info
[1]
Nanobody anti-VGLUT1 clone 8 Research Inhibitor N.A. Biochemical agents
SBP Info
[1]
Nanobody anti-VGLUT1 clone 9 Research Inhibitor N.A. Tools for cell biology and neuroscience
SBP Info
[1]
References
1 Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport. Biochemistry. 2017 Aug 1;56(30):3962-3971.