Details of the BTS

General Information of Binding Target of SBP (BTS) (ID: ST00180)
BTS Name
CD16A
Synonyms
Fragment
BTS Type
Protein
Gene Name
FCGR3A
Organism
Homo sapiens (Human)
UniProt ID
A0A2H4Z8E3
UniProt Entry
A0A2H4Z8E3_HUMAN
PFam
PF13895
Sequence
WLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDS
GSYFCRGLXGSKNVSSETVNITITQ
Sequence Length
85
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Human VH dAb anti-CD16A VH D6 Research Activator EC50: 4 nM Cancers [ICD-11: 2D4Z]
SBP Info
 		[1], [2]
Human VH dAb anti-CD16A VH E11 Research Activator EC50: 8 nM Cancers [ICD-11: 2D4Z]
SBP Info
 		[1], [2]
References
1 Identification of high-affinity anti-CD16A allotype-independent human antibody domains. Exp Mol Pathol. 2016 Oct;101(2):281-289.
2 Construction of a large phage-displayed human antibody domain library with a scaffold based on a newly identified highly soluble, stable heavy chain variable domain. J Mol Biol. 2008 Oct 10;382(3):779-89.