Details of the BTS

General Information of Binding Target of SBP (BTS) (ID: ST00179)
BTS Name
Alpha-amylase
Synonyms
EC 3.2.1.1; Fragment
BTS Type
Protein
Family
Glycosyl hydrolase 13 family
Gene Name
AMY1A
Organism
Homo sapiens (Human)
UniProt ID
Q5T085
UniProt Entry
Q5T085_HUMAN
PFam
PF00128
Sequence
MKLFWLLFTIGFCWAQYSSNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPP
NENVAIHNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGN
AVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLSGL
LDLALGKDYVRSKIAEYMNHLIDIGVAGFRIDASKHMWPGDIKAIL
Sequence Length
226
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Human VH dAb anti-Alpha-amylase huVHAm416 Research Binder Kd: 4000 nM Research tool
SBP Info
 		[1]
Tendamistat-based binder anti-mAbA8/Alpha-amylase A8-7 Research Inhibitor N.A. Research tool
SBP Info
 		[2]
References
1 Aggregation-resistant VHs selected by in vitro evolution tend to have disulfide-bonded loops and acidic isoelectric points. Protein Eng Des Sel. 2009 Feb;22(2):59-66.
2 Tendamistat as a scaffold for conformationally constrained phage peptide libraries. J Mol Biol. 1995 Jul 21;250(4):460-70.