Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00146) | ||||||
|---|---|---|---|---|---|---|
| BTS Name |
Cell surface A33 antigen
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| Synonyms |
Glycoprotein A33
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| BTS Type |
Protein
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| Gene Name |
GPA33
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| Organism |
Homo sapiens (Human)
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| Function |
May play a role in cell-cell recognition and signaling.
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Gene ID | ||||||
| Sequence |
MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDK
LLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVS LMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNI LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVG IAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDD YRQEEQRSTGRESPDHLDQ |
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| Sequence Length |
319
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| DART anti-GPA33/CD3 MGD007 | Research | Binder | N.A. | Metastatic colorectal cancer [ICD-11: 2B91.Z] | [1] | |