Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00102) | ||||||
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| BTS Name |
Interleukin-17A
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| Synonyms |
IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8
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| BTS Type |
Protein
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| Family |
IL-17 family
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| Gene Name |
Il17a
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| Organism |
Mus musculus (Mouse)
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| Function |
Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6 (By similarity).
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Gene ID | ||||||
| Sequence |
MSPGRASSVSLMLLLLLSLAATVKAAAIIPQSSACPNTEAKDFLQNVKVNLKVFNSLGAK
VSSRRPSDYLNRSTSPWTLHRNEDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQ EILVLKREPESCPFTFRVEKMLVGVGCTCVASIVRQAA |
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| Sequence Length |
158
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Centyrin anti-IL-17A TP1-C6 | Research | Inhibitor | Kd: 1.8 nM | Research tool | [1] | |