Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00049) | ||||||
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| BTS Name |
Endoglucanase D
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| Synonyms |
EGD; EC 3.2.1.4; Cellulase D; Endo-1,4-beta-glucanase; Fragment
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| BTS Type |
Protein
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| Family |
Glycosyl hydrolase 9 (cellulase E) family
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| Gene Name |
celD
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| Organism |
Hungateiclostridium thermocellum (Clostridium thermocellum)
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| Function |
This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Sequence |
SLTGVFPSGLIETKVSAAKITENYQFDSRIRLNSIGFIPNHSKKATIAANCSTFYVVKED
GTIVYTGTATSMFDNDTKETVYIADFSSVNEEGTYYLAVPGVGKSVNFKIAMNVYEDAFK TAMLGMYLLRCGTSVSATYNGIHYSHGPCHTNDAYLDYINGQHTKKDSTKGWHDAGDYNK YVVNAGITVGSMFLAWEHFKDQLEPVALEIPEKNNSIPDFLDELKYEIDWILTMQYPDGS GRVAHKVSTRNFGGFIMPENEHDERFFVPWSSAATADFVAMTAMAARIFRPYDPQYAEKC INAAKVSYEFLKNNPANVFANQSGFSTGEYATVSDADDRLWAAAEMWETLGDEEYLRDFE NRAAQFSKKIEADFDWDNVANLGMFTYLLSERPGKNPALVQSIKDSLLSTADSIVRTSQN HGYGRTLGTTYYWGCNGTVVRQTMILQVANKISPNNDYVNAALDAISHVFGRNYYNRSYV TGLGINPPMNPHDRRSGADGIWEPWPGYLVGGGWPGPKDWVDIQDSYQTNEIAINWNAAL IYALAGFVNYNSPQNEVLYGDVNDDGKVNSTDLTLLKRYVLKAVSTLPSSKAEKNADVNR DGRVNSSDVTILSRYLIRVIEKLPI |
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| Sequence Length |
625
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Affitin anti-CelD E12 | Research | Inhibitor | Kd: 98 nM | Tools for inhibiting of glycosidases | [1] | |
| Affitin anti-CelD H3 | Research | Inhibitor | Kd: 48 nM | Tools for inhibiting of glycosidases | [1] | |