General Information of Synthetic Binding Protein (SBP) (ID: SBP003481)
SBP Name
EGFRc minibinder
Synonyms
EGFRc_mb
Molecular Weight 7.4 kDa
Thermal Denaturation TEMP 71.2 ℃
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Yeast display
Highest Status Research
Sequence Length 63
SBP Sequence
>EGFRc minibinder
SLDEAKKLLQEAEKLARKLNDRMELAYVEFLKHILETAKKQNDKRTIESVRDMARDALEE
LQS
3D Structure
Computationally Modelled Structure
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Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Epidermal growth factor receptor
BTS Info
binder Research tool Kd: 6.8 nM University of Washington [1]
References
1 Design of protein-binding proteins from the target structure alone