General Information of Synthetic Binding Protein (SBP) (ID: SBP003290)
SBP Name
scFv anti-MG-2p HL4-MG
Synonyms
scFv HL4-MG
Molecular Weight 26.1 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Yeast
Selection Method Yeast display
Highest Status Research
Sequence Length 280
SBP Sequence
>scFv anti-MG-2p HL4-MG
LQASGGGGSGGGGSASQVQLVESEGGLVQPGGSLRLSCAASGFTFSSYEMNWVRQAPGKG
LEWVSRIDGDGSSTNYADSVKGRFTISRDNAKSTLYLQMNSLRAEDTAVYYCTRARYFGS
VSPYGMDVWGQGTTVTVSSGILGSGGGGSGGGGSGGGGSDIRVTQSPSSVSASVGDRVTI
SCRASQGIATWLGWYQQKPGKPPQLLIYSASTLQTGVPSRFSGSGSGTDFTLTISSLQPE
DVATYYCQEGSTFPLTFGGGTKVDIKSGILEQKLISEEDL
3D Structure
Computationally Modelled Structure
Click to Save PDB File
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
MG-2p
BTS Info
Binder Research tool Kd: 3.2 nM Carnegie Mellon University [1]
References
1 Fluorogen-activating single-chain antibodies for imaging cell surface proteins. Nat Biotechnol. 2008 Feb;26(2):235-40.