General Information of Synthetic Binding Protein (SBP) (ID: SBP003270)
SBP Name
scFv anti-C3AR E10
Synonyms
scFv E10
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Differential panning on cellulose sheets
Highest Status Research
Sequence Length 253
SBP Sequence
>VH Chain
QVQLKESGPGLVAPSQSLSITCTVSGFPLTSHGVSWVRQPPGKGLEWLGVIWGDGNTKYH
SALISRLSISKDNSKGQVFLKLNSLQTEDTATYYCARHYYKYANYAMDYWGQGTSVTVSS
G
>VL Chain
DIKMTKSQKFMSTSVGDRVSVTCKASQNVGTNVAWYQQKPGQSPKALIYSASYRYSGVPD
RFTGSGSGTDFTLTISNVQSEDLAEYFCQQYNSYPLTFGAGTKLELK
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
C3a anaphylatoxin chemotactic receptor
BTS Info
Binder Research tool N.A. Medical School Hannover [1]
References
1 Site-specific anti-C3a receptor single-chain antibodies selected by differential panning on cellulose sheets. Anal Biochem. 2001 Jun 1;293(1):142-5.