General Information of Synthetic Binding Protein (SBP) (ID: SBP003100)
SBP Name
scFv anti-BoNT/A AR4
Synonyms
scFv AR4
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Yeast display
Highest Status Research
Template Name scFv HuC25
Template Sequence
>H1
TFSDYYMH; L2
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Botulinum neurotoxin type A
BTS Info
Binder Botulism [ICD-11: 1A11.Z] Kd: 0.02 nM University of California [1]
References
1 Molecular evolution of antibody affinity for sensitive detection of botulinum neurotoxin type A. J Mol Biol. 2005 Aug 5;351(1):158-69.