General Information of Synthetic Binding Protein (SBP) (ID: SBP003092)
SBP Name
scFv anti-Burkholderia mallei clone M5D
Synonyms
scFv mallei M5D
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli TG1
Selection Method Phage display
Highest Status Research
SBP Sequence
>VH Chain
EVQLQQSGAELVRPGTSVKVSCKASGYAFTNYLIEWVKQRPGQGLEWIGVISPGGGSTNY
NEKFKGKATLTADKSSSTAYMQLSSLTSDDSAVYFCARLWFYEVDYWGQGTSVTVSA
>VL Chain
QAVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQEKPDHLFTGLIDGTNNRAPGV
PARFSGSLIGDKAALTITGAQTEDEAIYFCALLYSNHWVFGGGTKLTVLG
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Burkholderia mallei
BTS Info
Binder Research tool N.A. Department of Environmental and Infectious Disease Sciences [1]
References
1 Improvement of anti-Burkholderia mouse monoclonal antibody from various phage-displayed single-chain antibody libraries. J Immunol Methods. 2011 Sep 30;372(1-2):146-61.