General Information of Synthetic Binding Protein (SBP) (ID: SBP003090)
SBP Name
scFv anti-Burkholderia pseudomallei clone P7C6
Synonyms
scFv P7C6
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli TG1
Selection Method Phage display
Highest Status Research
SBP Sequence
>VH Chain
QVKLQQSGGGLVQPGGSMKLSCAASGFTFSDAWMDWVRQSPEKGLEWVAEIRDKANNHAT
YYAESVKGRFTISRDDSKSSVYLQMNSLRAEDTGIYYCTRAGGAMDYWGQGTTVTVSS
>VL Chain
DIELTQSPASLAVSLGQRATISYRASKSVSTSGYSYMHWNQQKPGQPPRLLIYLVSNLES
GVPARFSGSGSGTDFTLNIHPVEEEDAATYYCQHIREAYTFGGGTKLEIKR
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Burkholderia pseudomallei
BTS Info
Binder Research tool N.A. Department of Environmental and Infectious Disease Sciences [1]
References
1 Improvement of anti-Burkholderia mouse monoclonal antibody from various phage-displayed single-chain antibody libraries. J Immunol Methods. 2011 Sep 30;372(1-2):146-61.