Details of the SBP

General Information of Synthetic Binding Protein (SBP) (ID: SBP003075)
SBP Name
scFv anti-HS MP3A5
Synonyms
scFv MP3A5
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli TG1
Selection Method Phage display
Highest Status Research
SBP Sequence
>CDR3
GNQQRH
Template Name scFv HS4C3
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1] , [2]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Heparan sulfate
BTS Info
Binder Research tool N.A. Radboud university [1] , [2]
References
1 Construction and evaluation of an antibody phage display library targeting heparan sulfate. Glycoconj J. 2020 Aug;37(4):445-455.
2 Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney. J Biol Chem. 1998 May 22;273(21):12960-6.