Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001866) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
BiTE anti-TfR/CD3
|
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| Synonyms |
TfR-BiTE
|
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| Molecular Weight | 56 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS018 | [1] | ||||
| Scaffold Name | BiTE | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Transferrin receptor protein 1 | Binder | Solid tumour/cancer [ICD-11: 2A00-2F9Z] | N.A. | Tongji Medical College | [1] | |
| T-cell surface glycoprotein CD3 | Binder | Solid tumour/cancer [ICD-11: 2A00-2F9Z] | N.A. | Tongji Medical College | [1] | |