Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001851) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-EGFRvIII
|
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| Synonyms |
Anti-EGFRvIII scFv
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Epidermal growth factor receptor | Binder | Glioblastoma [ICD-11: XH7F82] | N.A. | National Cancer Institute | [1] | |