General Information of Synthetic Binding Protein (SBP) (ID: SBP001848)
SBP Name
scFv anti-Rh system clone D7
Synonyms
scFv D7
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
SBP Sequence
>VL CDR1
RASQSSSSYLN
>VL CDR2
AASSLQS
>VL CDR3
QQSYSTPPT
Template Name scFv E3
Template Sequence
>VL CDR1
QGDSLRSYYAS
>VL CDR2
GKNNRPS
>VL CDR3
NSRDSSGNH
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Rh system E antigen
BTS Info
Binder Tools for synthesis of Rh Fv phage-antibodies N.A. Molecular Immunopathology Unit and Centre for Protein Engineering [1]
References
1 Synthesis of Rh Fv phage-antibodies using VH and VL germline genes. Br J Haematol. 1999 Jun;105(3):811-6.