Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001797) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-IBV ZL.10
|
|||||
| Synonyms |
scFv ZL.10
|
|||||
| Molecular Weight | 24.0 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli JM109 | |||||
| Highest Status | Research | |||||
| Sequence Length | 239 | |||||
| SBP Sequence |
>scFv anti-IBV ZL.10
AVTLDESGGGLQTPGGALSLVCKGSGFTFSSHGMGWVRQAPGKGLEYVAAISSTGTYTNY GAAVKGRATISRDNGQSTVRLQLSNLRAEDTGTYYCAKSAGGRWYPYNIDAWGHGTEVIV SSGGGGSGGGGSGGGGSLTQPSSVSANLGGTVEITCSGGTSNYGWYQQKAPGSAPVTVIY ANTNRPSNIPSRFSGSTSGRTTNTLTITGVQAEDEAVYFCGAYDGGTSTFGAGTTLTVL |
|||||
| 3D Structure | ||||||
| Computationally Modelled Structure | ||||||
| Click to Save PDB File | ||||||
| Template Name | Germline VH and VL | |||||
| Template Sequence |
>VH Chain
AVTLDESGGGLQTPGGALRLVCKASGFTFSSYDMLWVRQAPGKGLEFVAGIDNTGSYTNY GAAVKGRATISRDNGQSTGRLQLNNLRAEDTATYYCAKRTAGSIDAWGHGTEVIVSS >VL Chain LTQPSSVSANPGGTVKITCSGDSSYYGWYQQKAPGSAPVTVIYDNTNRPSNIPSRFSGSK SGSTATLTITGVRADDNAVYYCASTDSSSTAGIFGAGITLTVL |
|||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Spike glycoprotein | Inhibitor | Infectious bronchitis virus infection(IBV infection) | N.A. | Shanghai Jiaotong University | [1] | |