Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001795) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-Abeta A4
|
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| Synonyms |
scFv A4
|
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| Molecular Weight | 29 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli HB2151 | |||||
| Selection Method | Phage display and Atomic force microscopy | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Amyloid-beta precursor protein | Inhibitor | Alzheimer disease [ICD-11: 8A20] | N.A. | Arizona State University | [1] | |