General Information of Synthetic Binding Protein (SBP) (ID: SBP001794)
SBP Name
scFv anti-Abeta c23.5
Synonyms
scFv c23.5
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Yeast
Selection Method Yeast display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Amyloid-beta precursor protein
BTS Info
Binder Alzheimer disease [ICD-11: 8A20] N.A. Arizona State University [1]
References
1 Promoting alpha-secretase cleavage of beta-amyloid with engineered proteolytic antibody fragments. Biotechnol Prog. Jul-Aug 2009;25(4):1054-63.