General Information of Synthetic Binding Protein (SBP) (ID: SBP001779)
SBP Name
scFv anti-Melanoma cell 718
Synonyms
scFv 718
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli TG1
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Breast cancer cells
BTS Info
Binder Breast cancer [ICD-11: 2C6Z]; Melanoma [ICD-11: 2C30] N.A. University of Vermont [1]
Melanoma cells
BTS Info
Binder Breast cancer [ICD-11: 2C6Z]; Melanoma [ICD-11: 2C30] N.A. University of Vermont [1]
References
1 Selection of tumor-binding ligands in cancer patients with phage display libraries. Cancer Res. 2006 Aug 1;66(15):7724-33.