Details of the SBP | SYNBIP

General Information of Synthetic Binding Protein (SBP) (ID: SBP001774)
SBP Name	scFv anti-IFN A6
Synonyms	scFv A6
Molecular Weight	27.9 kDa
Design Method	Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System	Escherichia coli HB2151
Selection Method	Phage display
Highest Status	Research

Protein Scaffold Information of This SBP
Scaffold ID	PS057 Scaffold Info					[1]
Scaffold Name	scFv
Scaffold Class	Antibody fragment
Fold Type	Beta-Sheets + Loops

Binding Target(s) of This SBP (BTS)

BTS Name	Details	Mechanism	Application	Affinity	Research Organization	Ref
Interferon gamma receptor 1	BTS Info	Binder	Research tool	Kd: 12 nM	University of Zurich	[1]
Interferon gamma receptor 1	BTS Info	Binder	Research tool	Kd: 0.02 nM	University of Zurich	[1]

References

1

Analysis of antibody A6 binding to the extracellular interferon gamma receptor alpha-chain by alanine-scanning mutagenesis and random mutagenesis with phage display. Biochemistry. 2000 Dec 26;39(51):15674-85.