Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001706) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-HIV-1 clone X5
|
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| Synonyms |
scFv X5
|
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Envelope glycoprotein gp160 | Inhibitor | Human immunodeficiency virus type 1 infection [ICD-11: XN8LD] | Kd: 2.5 nM | National Cancer Institute-Frederick | [1] | |
| HIV gp120-sCD4 complex | Inhibitor | Human immunodeficiency virus type 1 infection [ICD-11: XN8LD] | Kd: 0.085 nM | National Cancer Institute-Frederick | [1] | |