General Information of Synthetic Binding Protein (SBP) (ID: SBP001703)
SBP Name
scFv anti-BHL clone B1
Synonyms
scFv B1
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli BL21
Selection Method Phage display
Highest Status Research
SBP Sequence
>VH CDR3
FWHQYS
>VL CDR3
QQKSDEPQ
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
T-cell surface glycoprotein CD3
BTS Info
Binder Ovarian cancer [ICD-11: 2C73.Z] N.A. Chinese Academy of Sciences [1]
Anti-ovarian carcinoma bispecific Antibody
BTS Info
Binder Ovarian cancer [ICD-11: 2C73.Z] N.A. Chinese Academy of Sciences [1]
References
1 Construction of a fully synthetic human scFv antibody library with CDR3 regions randomized by a split-mix-split method and its application. J Biochem. 2008 Nov;144(5):591-8.