General Information of Synthetic Binding Protein (SBP) (ID: SBP001668)
SBP Name
scFv anti-PA M18
Synonyms
scFv M18
Molecular Weight 26.2 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method APEx two-hybrid
Highest Status Research
Sequence Length 247
SBP Sequence
>scFv anti-PA M18
DIVLIQSTSSLSASLGDRVTVSCRASQDIRNYLNWYQQKPDGTVKFLIYYTSRLQPGVPS
RFSGSGSGTDYSLTINNLEQEDIGTYFCQQGNTPPWTFGGGTKLEIKRGGGGSGGGGSGG
GGSGGGGSEVQLQQSGPELVKPGASVKISCKDSGYAFNSSWMNWVKQRPGQGPEWIGRIY
PGDGDSNYNGKFEGKAILTADKSSSTAYMQLSSLTSVDSAVYFCARSGLLRYAMDYWGQG
TSVTVSS
3D Structure
Computationally Modelled Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Protective antigen
BTS Info
Binder Research tool N.A. University of Texas [1]
References
1 APEx 2-hybrid, a quantitative protein-protein interaction assay for antibody discovery and engineering. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8247-52.