General Information of Synthetic Binding Protein (SBP) (ID: SBP001666)
SBP Name
scFv anti-AHSV-3 Lca12
Synonyms
scFv Lca12
Molecular Weight 28.1 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Phage display
Highest Status Research
Sequence Length 276
SBP Sequence
>scFv anti-AHSV-3 Lca12
MLLLAAQPALMAAVTLDESGGGLQTPGGGLSLICKASGFDFSSYPMGWVRQAPGKGLEWV
ADIDGDGSGTYYGAAVKGRATISRDDGQSTVRLQLNNLRAEDTATYYCAKTTGNSWTAGK
IDAWGHGTEVIVSFGGGGSGGGGSGGGGSALTQPSSVSANPGETVKITCSGSDSSYGYYG
WYQQKSPGSALVTVIYWDDERPSGIPSRFSGSTSGSTATLTITGVQVEDEAVYYCGNADS
SYDGIFGAGTTLTVLGQPNAAAEQKLISEEDLNGAA
3D Structure
Computationally Modelled Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
African horsesickness virus 3
BTS Info
Binder African horse sickness virus infection N.A. Onderstepoort Veterinary Institute [1]
References
1 A large semi-synthetic single-chain Fv phage display library based on chicken immunoglobulin genes. BMC Biotechnol. 2004 Apr 1;4:6.