Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001654) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
scFv anti-HIV-1 clone 1-25
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| Synonyms |
scFv 1-25
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| Template Name | scFv D5 | |||||
| Template Sequence |
>Heavy Chain
QVQLVQSGAEVRKPGASVKVSCKASGDTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANY AQKGRVTITADESTSTAYMELSSLRSEDTAIYYCARDNPTLLGSDYWGKGTLVTVSS >Light Chain DIQMTQSPSTLSASIGDRVTITCRASEGIYHWLAWYQQKPGKAPKLLIYKASSLASGAPS RFSGSGTDFTLTISSLQPDDFATYYCQQYSNYPLTFGGGTKLEIKRA |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS057 | [1] | ||||
| Scaffold Name | scFv | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Envelope glycoprotein gp160 | Binder | Human immunodeficiency virus type 1 infection [ICD-11: XN8LD] | N.A. | Merck Research Laboratories | [1] | |