General Information of Synthetic Binding Protein (SBP) (ID: SBP001640)
SBP Name
scFv anti-HIV-1 1G8C
Synonyms
scFv 1G8C
Molecular Weight 32 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli HB2151
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Envelope glycoprotein gp160
BTS Info
Binder Human immunodeficiency virus type 1 infection [ICD-11: XN8LD] N.A. All India Institute of Medical Sciences [1]
References
1 A novel strategy for efficient production of anti-V3 human scFvs against HIV-1 clade C. BMC Biotechnol. 2012 Nov 15;12:87.