General Information of Synthetic Binding Protein (SBP) (ID: SBP001633)
SBP Name
scFv anti-CD146 B6-11
Synonyms
scFv B6-11
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli TG1
Selection Method Phage display
Highest Status Research
SBP Sequence
>VH CDR3
SSNVRT
>VL CDR3
TPLSAP
Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Cell surface glycoprotein MUC18
BTS Info
Binder Research tool N.A. Medical University of Vienna [1]
References
1 Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display. PLoS One. 2015 May 20;10(5):e0127169.