General Information of Synthetic Binding Protein (SBP) (ID: SBP001619)
SBP Name
scFv anti-EYMPME 3D5
Synonyms
scFv 3D5
Molecular Weight 26.5 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
PDB ID 1KTR
Sequence Length 250
SBP Sequence
>scFv anti-EYMPME 3D5
DYKDILMTQTPSSLPVSLGDQASISCRSSQSIVHSNGNTYLEWYLQKPGQSPKLLIYKVS
NRFSGVPDRFSGSGSGTDFTLKISRVEAEDLGVYYCFQGSHVPFTFGSGTKLEIKRGGGG
SGGGGSGGGGSGGGGSQVQLQQSGPEDVKPGASVKISCKASGYTFTDYYMNWVKQSPGKG
LEWIGDINPNNGGTSYNQKFKGRATLTVDKSSSTAYMELRSLTSEDSSVYYCESQSGAYW
GQGTTVTVSA
3D Structure
Experimentally Validated Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS057
Scaffold Info
[1]
Scaffold Name scFv
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
EE peptide
BTS Info
Binder Tools as chaperones Kd: 4700 nM University of Texas at Austin [1]
References
1 Conversion of scFv peptide-binding specificity for crystal chaperone development. Protein Eng Des Sel. 2011 May;24(5):419-28.