General Information of Synthetic Binding Protein (SBP) (ID: SBP001589)
SBP Name
Fab anti-HSV Fab 1
Synonyms
Fab 1
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli XL1-Blue
Selection Method Phage display
Highest Status Research
SBP Sequence
>Heavy Chain CDR3
QRTHSRVTYFAASEFDP
Protein Scaffold Information of This SBP
Scaffold ID PS034
Scaffold Info
[1]
Scaffold Name Fab
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Herpes simplex virus
BTS Info
Binder Herpes simplex virus infection [ICD-11: 1F00.Z] N.A. Catholic University of the Sacred Heart [1]
References
1 A new subtraction technique for molecular cloning of rare antiviral antibody specificities from phage display libraries. Res Virol. Sep-Oct 1998;149(5):327-30.