General Information of Synthetic Binding Protein (SBP) (ID: SBP001583)
SBP Name
Fab anti-Integrin clone 9
Synonyms
Fab-9
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS034
Scaffold Info
[1]
Scaffold Name Fab
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Integrin alpha-v-beta-3
BTS Info
Binder Research tool N.A. The Scripps Research Institute [1]
References
1 Integrin alphaIIbbeta3-specific synthetic human monoclonal antibodies and HCDR3 peptides that potently inhibit platelet aggregation. FASEB J. 2004 Feb;18(2):361-3.