General Information of Synthetic Binding Protein (SBP) (ID: SBP001525)
SBP Name
Fab anti-RNA BL1
Synonyms
Fab BL1
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS034
Scaffold Info
[1]
Scaffold Name Fab
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
RNA
BTS Info
Binder Research tool Kd: 500 nM University of Chicago [1]
References
1 Crystal structure of an RNA polymerase ribozyme in complex with an antibody fragment. Philos Trans R Soc Lond B Biol Sci. 2011 Oct 27;366(1580):2918-28.