General Information of Synthetic Binding Protein (SBP) (ID: SBP001520)
SBP Name
Fab anti-HIV-1 m0
Synonyms
Fab m0
Molecular Weight 60 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS034
Scaffold Info
[1]
Scaffold Name Fab
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Envelope glycoprotein gp160
BTS Info
Binder Cancers [ICD-11: 2D4Z] N.A. National Cancer Institute-Frederick [1]
References
1 Construction of a large phage-displayed human antibody domain library with a scaffold based on a newly identified highly soluble, stable heavy chain variable domain. J Mol Biol. 2008 Oct 10;382(3):779-89.