General Information of Synthetic Binding Protein (SBP) (ID: SBP001519)
SBP Name
Fab anti-Hendra virus m102.4
Synonyms
Fab m102.4
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli TG1
Selection Method Phage display
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS034
Scaffold Info
[1]
Scaffold Name Fab
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Attachment glycoprotein
BTS Info
Inhibitor Hendra virus infection [ICD-11: XN53N] N.A. National Cancer Institute-Frederick [1]
References
1 Exceptionally potent cross-reactive neutralization of Nipah and Hendra viruses by a human monoclonal antibody. J Infect Dis. 2008 Mar 15;197(6):846-53.