Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001511) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Fab anti-CD98 B3
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| Synonyms |
Fab B3
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>Heavy Chain
QVKLLESGPSLVQPSQSLSITCTVSGFSLTTYGLHWVRQPPGKGLEWLGVIWSNGRIDYN AAFISRLSITKINSKSQVFFKHNSLQDDDTAIYYCARNVYDSLTWFTYWGQGTLVTVSA >Light Chain DIVMSQSPSSLAVSVGEKVIMSCKSSQSLLYSSNQKNYLAWYQQKPGQSPKLLIYWASTR ESGVPDRFTGSGSGTDFTLTISSVKAEDLAAYYCQQYYSYPPTFGGGTKLEIKRA |
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| Template Name | HBJ127 | |||||
| Template Sequence |
>Heavy Chain
QVKLLESGPGLVQPSQSLSITCTVSGFSLTTYGLHWVRQPPGKGLEWLGVIWSNGRIDYN AAFISRLSITKINSKSQVFFKHNSLQDDDTAIYYCARNVYDSLTWFTY WGQGTLVTVSA >Light Chain DIQMTQSPSSLAVSVGEKVIMICKSSQSLLYSSNQKNYLAWYQQKPGQSPKLLIFWASTR ESGVPDRFTGSGSGTDFPLTISSVKAEDLAVYFCQQYYIYPPTFGGGTKLEIKRA |
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| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS034 | [1] | ||||
| Scaffold Name | Fab | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
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| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| 4F2 cell-surface antigen heavy chain | Binder | Tumors [ICD-11: XH1N44] | N.A. | University of Shizuoka | [1] | |