Details of the SBP
General Information of Synthetic Binding Protein (SBP) (ID: SBP001510) | ||||||
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SBP Name |
Fab anti-CD98 A18
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Synonyms |
Fab A18
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Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
Selection Method | Phage display | |||||
Highest Status | Research | |||||
SBP Sequence |
>Heavy Chain
QVKLLESGGGLVQPSQSLSITCTVSGFSLTTYGLHWVRQPPGKGLEWLGVIWSNGRIDYN AAFISRLSITKINSKSQVFFKHNSLQDDDTAIYYCARNVYDSLTWFTYWGQGTLVTVSA >Light Chain DIQMTQTPSSLAVSVGEKVIMSCKSSQSLLYSSNQKNYLAWYQQKPGQSPKLLIYWASTR ESGVPDRFTGSGSGTDFTLTISSVKAEDLAVYYCQQYYSYPPTFGGGTKLEIKRA |
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Template Name | HBJ127 | |||||
Template Sequence |
>Heavy Chain
QVKLLESGPGLVQPSQSLSITCTVSGFSLTTYGLHWVRQPPGKGLEWLGVIWSNGRIDYN AAFISRLSITKINSKSQVFFKHNSLQDDDTAIYYCARNVYDSLTWFTY WGQGTLVTVSA >Light Chain DIQMTQSPSSLAVSVGEKVIMICKSSQSLLYSSNQKNYLAWYQQKPGQSPKLLIFWASTR ESGVPDRFTGSGSGTDFPLTISSVKAEDLAVYFCQQYYIYPPTFGGGTKLEIKRA |
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Protein Scaffold Information of This SBP | ||||||
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Scaffold ID | PS034 | [1] | ||||
Scaffold Name | Fab | |||||
Scaffold Class | Antibody fragment | |||||
Fold Type | Beta-Sheets + Loops | |||||
Binding Target(s) of This SBP (BTS) |
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BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
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4F2 cell-surface antigen heavy chain | Binder | Tumors [ICD-11: XH1N44] | N.A. | University of Shizuoka | [1] | |