Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001277) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Monobody anti-Erk-2 F6.2
|
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| Synonyms |
Monobody F6.2
|
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| Thermal Denaturation TEMP | 69 ℃ | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Human embryonic kidney?cells 293 | |||||
| Selection Method | Yeast display | |||||
| Highest Status | Research | |||||
| SBP Sequence |
>BC Loop
RSHGSVYY >DE Loop FWVSN >FG Loop GPFRRCSSSH |
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| Template Name | 10th domain of fibronectin type III (10Fn3) | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS047 | [1] | ||||
| Scaffold Name | Monobody | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 1 | Inhibitor | Research tool | Kd: 12.4 nM | University at Buffalo | [1] | |