General Information of Synthetic Binding Protein (SBP) (ID: SBP001185)
SBP Name
Monobody anti-SUMO clone 57
Synonyms
Monobody ySUMO-57
Molecular Weight 10.6 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Selection Method Phage display and Yeast display
Highest Status Research
Sequence Length 96
SBP Sequence
>Monobody anti-SUMO Slone 57
GSSVPTNLEVVAATPTSLLISWDAYYSYYSYSVSYYRITYGETGGNSPVQEFTVPYYYST
ATISGLKPGVDYTITVYAYSSYSSSSYSPISINYRT
3D Structure
Computationally Modelled Structure
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Template Name Fibronectin type III domain (FN3)
Protein Scaffold Information of This SBP
Scaffold ID PS047
Scaffold Info
[1]
Scaffold Name Monobody
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Yeast small ubiquitin-related modifier
BTS Info
Binder Research tool Kd: 9 nM University of Chicago [1]
References
1 High-affinity single-domain binding proteins with a binary-code interface. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6632-7.