Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001086) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Nanobody anti-IrtAB Syb_NL5
|
|||||
| Synonyms |
Syb_NL5
|
|||||
| Molecular Weight | 13.6 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli MC1061 | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| PDB ID | 6TEJ | |||||
| Sequence Length | 124 | |||||
| SBP Sequence |
>Nanobody anti-IrtAB Syb_NL5
GPSQVQLVESGGGLVQAGGSLRLSCAASGFPVSSSTMTWYRQAPGKEREWVAAINSYGYY TVYADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCNVKDTGQMRESYDYWGQGTQV TVSA |
|||||
| 3D Structure | ||||||
| Experimentally Validated Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS048 | [1] | ||||
| Scaffold Name | Nanobody | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| ABC transporter IrtAB | Binder | Mycobacterium tuberculosis [ICD-11: XN1N2] | Kd: 150 nM | University of Zurich | [1] | |