Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP001067) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Nanobody anti-BasC clone 74
|
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| Synonyms |
Nb74
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| Molecular Weight | 14.4 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | Escherichia coli WK6 | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| PDB ID | 6F2G; 6F2W | |||||
| Sequence Length | 134 | |||||
| SBP Sequence |
>Nanobody anti-BasC clone 74
QVQLVESGGGVVQAGGSLRLSCAASGRTFSSRAMGWFRQAPGEGREFVATISWSGSYTEY ADSVKGRVTISRDNAKNTVYLQMNSLKPGDTAVYHCAAKNGGAASNYPNDYVYWGQGTQV TVSSHHHHHHEPEA |
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| 3D Structure | ||||||
| Experimentally Validated Structure | ||||||
| Click to Save PDB File | ||||||
| Template Name | Chain A of PDBID 5H8D | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS048 | [1] | ||||
| Scaffold Name | Nanobody | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Bacterial alanine-serine-cysteine exchanger | Inhibitor | Research tool | Kd: 3.9 nM | Institute for Research in Biomedicine (IRB Barcelona) | [1] | |