General Information of Synthetic Binding Protein (SBP) (ID: SBP001060)
SBP Name
Nanobody anti-TmrAB clone 9F10
Synonyms
Nb9F10
Molecular Weight 13.3 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli TG1
Highest Status Research
PDB ID 6RAN
Sequence Length 126
SBP Sequence
>Nanobody anti-TmrAB clone 9F10
MAQLQLVESGGGLVQPGDSLRLSCAVSGSALDYNAIGWFRQAPGKEREGVACISKITGNT
AYADSVKGRFTISRDNAKNTVHLQMNSLKPEDTAVYYCATVTAVLLPGRCVPGKYWGQGT
PVTVSS
3D Structure
Experimentally Validated Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS048
Scaffold Info
[1]
Scaffold Name Nanobody
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Heterodimeric ABC exporter TmrAB
BTS Info
Binder Research tool N.A. Goethe University Frankfurt [1]
References
1 Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature. 2019 Jul;571(7766):580-583.