General Information of Synthetic Binding Protein (SBP) (ID: SBP001049)
SBP Name
Nanobody anti-TGP Anti-TGP clone 68
Synonyms
Anti-TGP Sb#68; Anti-TGP sybody 68; Synthetic anti-TGP nanobody 68
Molecular Weight 12.6 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Sequence Length 115
SBP Sequence
>Nanobody anti-TGP Anti-TGP clone 68
QVQLVESGGGLVQAGGSLRLSCAASGFPVNAVTMWWYRQAPGKEREWVAAIKSQGAGTWY
ADSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCHVYVGAYRYEGRGTQVTVS
3D Structure
Computationally Modelled Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS048
Scaffold Info
[1]
Scaffold Name Nanobody
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
Green fluorescent GFP-like protein
BTS Info
Binder Research tool Kd: 10.4 nM University of Zurich [1]
References
1 An improved fluorescent tag and its nanobodies for membrane protein expression, stability assay, and purification. Commun Biol. 2020 Dec 10;3(1):753.