General Information of Synthetic Binding Protein (SBP) (ID: SBP000893)
SBP Name
RPtag anti-peptide mutant
Synonyms
RPtag Nd2,P5A,E18A
Molecular Weight 2.1 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Highest Status Research
Sequence Length 19
SBP Sequence
>RPtag anti-peptide mutant
KIANFIPAELKLITKANVQ
3D Structure
Computationally Modelled Structure
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Template Name RPtag(small)
Protein Scaffold Information of This SBP
Scaffold ID PS056
Scaffold Info
[1]
Scaffold Name RPtag
Scaffold Class Non-Antibody
Fold Type Alpha-Helices + Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
RPtag(large)
BTS Info
Binder Research tool Kd: 0.047 nM Ichor Therapeutics, Inc; RecombiPure, Inc [1]
References
1 RPtag as an Orally Bioavailable, Hyperstable Epitope Tag and Generalizable Protein Binding Scaffold. Biochemistry. 2018 May 29;57(21):3036-3049.