General Information of Synthetic Binding Protein (SBP) (ID: SBP000302)
SBP Name
Macrocyclic peptide anti-TEV-protease CycTev1
Synonyms
Macrocyclic peptide CycTev1
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Expression System Escherichia coli
Selection Method Phage display
Highest Status Research
Sequence Length 8
SBP Sequence
>Macrocyclic peptide anti-TEV-protease CycTev1
CWRDYLIX
Sequence Description X represents N-acryloyl-lysine; Cys and X form a bridge.
3D Structure
Computationally Modelled Structure
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Protein Scaffold Information of This SBP
Scaffold ID PS044
Scaffold Info
[1]
Scaffold Name Macrocyclic peptide
Scaffold Class Non-Antibody
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
TEV protease
BTS Info
Binder Research tool Kd: 8200 nM Texas A&M University [1]
References
1 A Genetically Encoded, Phage-Displayed Cyclic-Peptide Library. Angew Chem Int Ed Engl. 2019 Oct 28;58(44):15904-15909.