Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000301) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Macrocyclic peptide anti-RANKL OP3-4
|
|||||
| Synonyms |
Macrocyclic peptide OP3-4
|
|||||
| Molecular Weight | 1.5 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Sequence Length | 11 | |||||
| SBP Sequence |
>Macrocyclic peptide anti-RANKL OP3-4
YCEIEFCYLIR |
|||||
| Sequence Description | Cys I and Cys II form disulfide bonds. | |||||
| 3D Structure | ||||||
| Computationally Modelled Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS044 | [1] , [2] | ||||
| Scaffold Name | Macrocyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Tumor necrosis factor ligand superfamily member 11 | Modulator | Cancers [ICD-11: 2D4Z] | Kd: 3890 nM | University of Pennsylvania | [1] , [2] | |
| References |
|---|