Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000299) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Macrocyclic peptide anti-Integrin ALOS4
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| Synonyms |
Macrocyclic peptide ALOS4
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| Molecular Weight | 0.9 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | Phage display | |||||
| Highest Status | Research | |||||
| Sequence Length | 9 | |||||
| SBP Sequence |
>Macrocyclic peptide anti-Integrin ALOS4
CFLSGASSC |
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| Sequence Description | Cys I and Cys II form disulfide bonds. | |||||
| 3D Structure | ||||||
| Computationally Modelled Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS044 | [1] | ||||
| Scaffold Name | Macrocyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Integrin alpha-v-beta-3 | Inhibitor | Cancers [ICD-11: 2D4Z] | Kd: 2550 nM | Ariel University | [1] | |